Regarding the use of tourniquets in the theatre
environment, the following statements
are true EXCEPT which one?
a) Exsanguination and tourniquet inflation is associated with immediate rise in
central venous pressure, arterial blood pressure and
heart rate
b) After two hours’ inflation time, a significant decrease in core
temperature can be
expected on deflation of the tourniquet
c) Pre-inflation, ketamine 0.25 mg/kg
intravenously can prevent the hypertensive
response to tourniquets
d) When using a double-cuff tourniquet for
intravenous regional anaesthesia the
proximal cuff is the first to be used
e) If the continuous tourniquet inflation time exceeds two hours, the ischaemic cell
damage and lesions associated with acidosis are
irreversible
Answer: e
Explanation
The use of a tourniquet for prevention of
haemorrhage during limb surgery requires a
pneumatic cuff of width at least half the diameter
of the limb. The limb is exsanguinated
and the cuff inflated to 50mmHg greater than the
systolic blood pressure for the
upper limb or 100mmHg greater than the systolic
blood pressure for the lower limb.
Exsanguination causes an autotransfusion of blood
volume to the central compartment
with consequent increase in central venous pressure,
heart rate and blood pressure.
This is exacerbated by the acute increase in
systemic vascular resistance. The temperature
of the ischaemic limb drops and metabolites
accumulate in it. It is the release of
these metabolites, and cold to the circulation,
which causes the physiological changes
seen on deflation. After about one hour of
cuff inflation, characteristic resistant hypertension
is seen. This may be avoided with pre-inflation ketamine as described or
regional anaesthesia. An arbitrary inflation duration limit of two hours is often applied
but some centres use in excess of this and at two
hours’ duration, cell lesions secondary
to local acidosis are reversible. During intravenous
regional anaesthesia the proximal
cuff is inflated first before the local
anaesthetic is injected in order that the site of the
distal cuff is rendered insensate before the distal
cuff is inflated such that tourniquet
pain is avoided.
Reference
Malanjum L, Fischer B. Procedures under tourniquet. Anaes Intens Care 2009; 10(1):
14–17.
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