Question: Pulmonary vasoconstriction may be caused by
a) Hypothermia
b) Smoking ‘Crack’ cocaine
c) Volatile anaesthetic agents
d) Calcium channel blockers
Answer: b
Explanation:
‘Crack’ or free-base cocaine is a Class
A illicit drug, which is used widely in the ‘hard’
drug taking community. In 2001, in the USA, 4.7% of
young adults admitted to having
used ‘Crack’ cocaine. Due to the illegal nature of the drug, ‘Crack’ has not been the
subject of formal randomised controlled trials.
There is a substantial body of case
reports and good animal-model work to suggest that
smoking ‘Crack’ puts a patient
at risk of developing pulmonary vasoconstriction.
All the other options here are known
to inhibit pulmonary vasoconstriction.
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