Regarding antiemetics, which one of the following
statements is TRUE?
a) Dexamethasone has been shown to downregulate 5-HT3 receptors in the
chemoreceptor trigger zone
b) As an anticholinergic, glycopyrrolate has useful
antiemetic properties
c) Cyclizine acts as an antiemetic by antagonism of
muscarinic acetylcholine receptors
d) Ondansetron exerts antagonism at 5-HT3 receptors only in the chemoreceptor
trigger zone and the nucleus tractus solitarius
e) Nabilone is an antagonist at endogenous
cannabinoid receptors
